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2型糖尿病肾病大鼠肾小管间质病变及TGF2β1、HGF和CTGF表达的变化及意义
www.yongyao.net  2009-7-27 9:41:07  来源:  责任编辑:
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4  参考文献
[ 1 ]  CaramoriM L, MauerM. Diabetes and nephropathy [ J ].CurrOp in Nephrol Hypertens, 2003, 12: 2732282.
[ 2 ]  ThomasM C, BurnsW C, CooperM E. Tubular changes inearly diabetic nephtopathy [ J ]. Adv Chronic Kidney Dis,2005, 12: 1772186.
[ 3 ]  L iu Y. Ep ithelial to mesenchymal transition in renal fibogenesis: pathologic significance, molecularmechanism, and therapeutic intervention[ J ]. J Am Soc Nephrol, 2004, 15:1212.
[ 4 ]  Cruzado J M, L loberas N, Torras J , et al. Regression of advanced diabetic nephropathy by hepatocyte growth factor gene therapy in rats[ J ]. Diabetes, 2004, 53: 111921127.
[ 5 ]  MorcosM, Sayed A A R, BierhansA, et al. Activation of tubular ep ithelial cells in diabetic nephropathy[ J ]. Diabetes, 2002, 51: 353223544.
[ 6 ]  Ziyadeh F N. Mediators of diabetic renal disease: the case for TGF2β as the major mediator[ J ]. J Am Soc Nephrol,2004, 15: S552S57.
[ 7 ]  Fraser D, Bruskill N, Ito T, et al. Long2term exposure ofp roximal tubular ep ithelial cells to glucose induces transforming growth factor2β1 synthesis via an autocrine PDGF loop[ J ]. Am J Pathology, 2003, 163: 256522574.
[ 8 ]  CohenM P, Ziyadeh F N, Hong SW, et al. Inhibiting albumin glycation in vivo ameliorates glomerular overexp ression of TGF2β1 [ J ]. Kidney International, 2002, 61: 202522032.
[ 9 ]  Morrisey K, Evans R A, Wakefield L, et al. Translational regulation of renal p roximal tubular ep ithelial cell transforming growth factor2β1 generation by insulin [ J ]. Am J Pathology, 2001, 159: 190521915.
[ 10 ] Lam S, van der Geest R N, Verhagen N A, et al. Secretion of collagen type IV by human renal fibroblasts is increased by high glucose via a TGF2TGF2β2independent pathway[ J ]. NephrolDia Transp lant, 2004, 19: 169421701.
[ 11 ] L i J H, Zhu H J , Huang X R, et al. Smad 7 inhibits fibrotic effect lf TGF2beta on renal tubular ep ithelial cells by blocking Smad 2 activation [ J ]. J Am Soc Nephrol, 2002,13: 146421472.
[ 12 ] 张春,朱忠华,刘建社,等. 结缔组织生长因子对肾小管上皮细胞转分化的调节机制[ J ]. 中华医学杂志, 2005,41: 292022925.
[ 13 ] 刘青娟,何宁,刘淑霞,等. 糖尿病肾病大鼠肾小管上皮细胞转化与肝细胞生长因子的表达[ J ]. 中国慢性病预防与控制, 2005, 13: 2662268.
[ 14 ] Nakagami H, Morishita R, Yamamoto K, et al. Hepatocyte growth factor p revents endothelial cell death through inhibition of bax translocation from cytosol to mitochondrial membrane[ J ]. Diabetes, 2002, 51: 260422611.
[ 15 ] Kagawa T, Takemura G, Kosai K, et al. Hepatocyte growth factor gene therapy slows down the p rogression of diabetic nephropathy in db /db mice [ J ]. Nephron Physiol, 2006,102: 922102.
[ 16 ] 钟慧,樊均明,李孜,等. 肝细胞生长因子对转化生长因子诱导肾小管上皮细胞转分化的影响[ J ]. 四川大学学报, 2005, 36: 6532656.
[ 17 ] Inoue T, Okada H, Kobayashi T, et al. Hepatocyte growth factor counteracts transforming growth factor2β1, through attenuation of connective tissue growth factor induction, andp revents renal fibrogenesis in 5 /6 nephrectomized mice[ J ].Faseb, 2003, 17: 2682270.


来源:首都医科大学学报    作者:安娜 刘惠兰 王英

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