中国公众合理用药援助系统
药品查询
请勾选查询条件后检索
药品名 企业名 批准文号 功能主治
你的位置:首页 > 药讯频道 > 药讯 > 学术科研 > 正文
减重外科进展
www.yongyao.net  2009-7-2 9:38:01  来源:  责任编辑:
分享到:

4 手术的现况与选择

理想的减重手术应包括以下几点[ 35 ] : ①危险性低:死亡率< 1% ,并发症率< 10%。②远期结果应至少使75%的病人减去多余体重的50%以上。③副作用少,术后生活质量好。④再手术率低,应每年小于2%。⑤手术可逆。目前最常用的减重手术为腹腔镜胃绕道术和腹腔镜可调节胃束带术。前者是美国减重手术的金标准,是目前最有效的减重手术,但此术式较复杂,有一定死亡率。后者是欧洲和澳洲的标准减重手术,已取代胃隔间术成为全世界最常用的减重手术,且是目前最安全的减重手术,几乎没有死亡率,但是效果较慢,需3年才能逐渐达到最大的效果。近年来由于腹腔镜技术的发展,腹腔镜限制型手术已是减重手术的首选,每年的手术急剧增加。目前全球每年施行减重手术约20万例,其中一半以上在美国完成,是美国最常见的胃肠道手术。

5 减重手术与美容手术的比较

需要强调的是,肥胖是疾病,治疗肥胖是治疗疾病。在西方,减重手术是可以用医疗保险支付的。减重手术不能等同于一般的美容手术,成功减重后全身各处的脂肪组织,包括腹腔内的脂肪均显著减少,血脂降低,各种伴随疾病如糖尿病、高血压、心脑血管疾病等均明显缓解甚至治愈。而美容手术,如抽脂术,虽可抽取高达10 kg的脂肪,但不会改善肥胖引起的各种健康危险因素,因此抽脂术绝不能作为减重手术,仅可作为局部瘦身的美容手术[ 36 ] 。

6 减重治疗应由专业团队完成

现在减重治疗应由包括营养师、理疗师、内科医师、外科医师和精神科医师的一个团队完成,减重手术还要有麻醉师参与。外科医师需经过严格培训、资格认证,还要在有丰富经验的医师帮助下完成一定例数后,方可单独进行这类手术,这是减少并发症和死亡率的关键之一。最近报告显示手术风险与医院每年完成的手术量有关,每年小于50例的医院死亡率为每年大于100 例医院的4倍[ 37 ] ,因此减重手术最好由有专业团队的医院、有经验的医师完成。

7 减重手术在我国的开展前景

减重手术在欧美、澳洲已是常见手术,在我国却开展得很少,并且我国尚无专业的减重外科医师。而我国目前有300万重度肥胖患者,是减重外科的对象,但他们却没有得到适当的治疗。从这两个角度看,减重外科在我国有很好的发展前景。

[参考文献]

[ 1 ]  WHO update: controlling the global obesity ep idemic [ EB /OL ].Accessed http: / /www. who. int/ nut/obs. htm, 200222227.

[ 2 ]  National Center forHealth Statistics. NHANES 1999 Prevalence ofoverweight and obesity among adults[ Z]. 1999.

[ 3 ]  Allison DB, Fontaine KR, Manson JE, et al. Annual deaths at2tributable to obesity in the United States[ J ]. JAMA, 1999, 282(16) : 153021538.

[ 4 ]  Thomp son D. Health care costs[ EB /OL ]. InnovusResearch. Ac2cessed http: / / cardiology. Medscape. com / reuters/p rof /2001 /06 /06. 01 /20010531econ001. html, 20012624.

[ 5 ]  中华医学会外科学分会内分泌外科学组,中华医学会外科学分会腹腔镜与内镜外科学组,中华医学会外科学分会胃肠外科学组,等. 中国肥胖病外科治疗指南(2007) [ J ]. 中国实用外科杂志, 2007, 27 (10) : 7592762.

[ 6 ]  Mokdad AH, Marks JS, Stroup DF, et al. Correction: actual cau2ses of death in the United States, 2000 [ J ]. JAMA, 2005, 293(3) : 2932294.

[ 7 ]  Wadden TA. Treatment of obesity by moderate and severe caloricrestriction. Results of clinical research trials [ J ]. Ann InternMed, 1993, 119 (7 Pt 2) : 6882693.

[ 8 ]  McMahon FG, Fujioka K, Singh BN, et al. Efficacy and safetyof sibutramine in obese white and African American patientswith hypertension: a 1 2year, double2blind, p lacebo2con2trolled, multicenter trial [ J ]. A rch Intern Med, 2000 , 160( 14 ) : 218522191.

[ 9 ]  Klein S. Medical management of obesity [ J ]. Surg Clin NorthAm, 2001, 81 (5) : 102521038.

[ 10 ] Garrow J. Christmas factor and snacking[ J ]. Lancet, 2000, 355(9197) : 8.

[ 11 ] Karlsson J, Sjêstrêm L, Sullivan M. Swedish obese subjects( SOS) an intervention study of obesity. Two2year follow2up ofhealth2related quality of life (HRQL ) and eating behavior aftergastric surgery for severe obesity[ J ]. Int J Obes RelatMetab Dis2ord, 1998, 22 (2) : 1132126.

[ 12 ] MacDonald KG J r, Long SD, SwansonMS, et al. The gastric by2pass operation reduces the p rogression and mortality of non2insulin2dependent diabetes mellitus [ J ]. J Gastrointest Surg, 1997, 1(3) : 2132220.

[ 13 ] LeeWJ, HuangMT, WangW, et al. Effects of obesity surgery onthe metabolic syndrome [ J ]. Arch Surg, 2004, 139 ( 10) : 108821092.

[ 14 ] N IH conference. Gastrointestinal surgery for severe obesity. Con2sensus Development Conference Panel [ J ]. Ann Intern Med,1991, 115 (12) : 9562961.

[ 15 ] HockingMP, DuersonMC, O’Leary JP, et al. Jejunoileal bypassformorbid obesity. Late follow2up in 100 cases [ J ]. N Engl JMed, 1983, 308 (17) : 9952999.

[ 16 ] Scop inaro N, Adami GF, Marinari GM, et al. Biliopancreatic di2version[ J ]. World J Surg, 1998, 22 (9) : 9362946.

[ 17 ] Marceau P, Hould FS, Simard S, et al. Biliopancreatic diversionwith duodenal switch[ J ]. World J Surg, 1998, 22 (9) : 9472954.

[ 18 ] Hess DS, Hess DW. Biliopancreatic diversion with a duodenalswitch[ J ]. Obes Surg, 1998, 8 (3) : 2672282.

[ 19 ] Mason EE. Vertical banded gastrop lasty for obesity [ J ]. ArchSurg, 1982, 117 (5) : 7012706.

[ 20 ] LeeWJ, HuangMT, Yu PJ, et al. Laparoscop ic vertical bandedgastrop lasty and laparoscop ic gastric bypass: a comparison [ J ].Obes Surg, 2004, 14 (5) : 6262634.

[ 21 ] Mason EE, Ito C. Gastric bypass in obesity[ J ]. Surg Clin NorthAm, 1967, 47 (6) : 134521351.

[ 22 ] Brolin RE, Kenler HA, Gorman JH, et al. Long2limb gastric by2pass in the superobese. A p rospective randomized study[ J ]. AnnSurg, 1992, 215 (4) : 3872395.

[ 23 ] Wittgrove AC, Clark GW, Schubert KR. Laparoscop ic Gastric By2pass, Roux2en2Y: Technique and Results in 75 PatientsWith 3230Months Follow2up [ J ]. Obes Surg, 1996, 6 (6) : 5002504.

[ 24 ] Schauer PR, Ikramuddin S, Gourash W, et al. Outcomes afterlaparoscop ic Roux2en2Y gastric bypass formorbid obesity[ J ]. AnnSurg, 2000, 232 (4) : 5152529.

[ 25 ] Kuzmak L I. A Review of Seven Years’ Experience with SiliconeGastric Banding[ J ]. Obes Surg, 1991, 1 (4) : 4032408.

[ 26 ] BelachewM, LegrandM, VincentV, et al. Laparoscop ic adjusta2ble gastric banding[ J ]. World J Surg, 1998, 22 (9) : 9552963.

[ 27 ] Ren CJ, Horgan S, Ponce J. US experience with the LAP - BANDsystem[ J ]. Am J Surg, 2002, 184 (6B) : 46S250S.

[ 28 ] 郑成竹,胡兵. 胃减容术治疗肥胖症[ J ]. 腹部外科, 2006, 19(1) : 9210.

[ 29 ] Chevallier JM, ZinzindohouéF, Elian N, et al. Adjustable gastricbanding in a public university hosp ital: p rospective analysis of 400patients[ J ]. Obes Surg, 2002, 12 (1) : 93299.[ 30 ] Fielding GA, RhodesM, Nathanson LK. Laparoscop ic gastricbanding formorbid obesity. Surgical outcome in 335 cases [ J ].Surg Endosc, 1999,13 (6) : 5502554.

[ 31 ] DeMaria EJ, Sugerman HJ, Meador JG, et al. High failure rateafter laparoscop ic adjustable silicone gastric banding for treatmentofmorbid obesity[ J ]. Ann Surg, 2001, 233 (6) : 8092818.

[ 32 ] Biertho L, Steffen R, Branson R, et al. Management of failed ad2justable gastric banding[ J ]. Surgery, 2005, 137 (1) : 33241.

[ 33 ] Zinzindohoue F, Chevallier JM, Douard R, et al. Laparoscop icgastric banding: a minimally invasive surgical treatment formorbidobesity: p rospective study of 500 consecutive patients [ J ]. AnnSurg, 2003, 237 (1) : 129.

[ 34 ] Mathus2Vliegen EM, Tytgat GN. Intragastric balloon for treatment2resistant obesity: safety, tolerance, and efficacy of 12year balloontreatment followed by a 12year balloon2free follow2up [ J ]. Gastroi2ntest Endosc, 2005, 61 (1) : 19227.

[ 35 ] Manterola C, Pineda V, VialM, et al. Surgery for morbid obesi2ty: selection of operation based on evidence from literature review[ J ]. Obes Surg, 2005, 15 (1) : 1062113.

[ 36 ] Klein S, Fontana L, Young VL, et al. Absence of an effect of li2posuction on insulin action and risk factors for coronary heart dis2ease[ J ]. N Engl J Med, 2004, 350 (25) : 254922557.

[ 37 ] Nguyen NT, Paya M, Stevens CM, et al. The relationship be2tween hosp ital volume and outcome in bariatric surgery at academicmedical centers[ J ]. Ann Surg, 2004, 240 (4) : 5862593.

免责声明:本文仅代表作者个人观点,与本网无关。转载目的在于传递更多信息,并不代表本网赞同其观点和对其真实性负责。对本文以及其中全部或者部分内容、文字的真实性、完整性、及时性本站不作任何保证或承诺,请读者仅作参考,并请自行核实相关内容。
返回资讯中心 返回资讯列表