基因多态性与心律失常

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参考文献
1　KeatingMT, SanguinettiMC. Molecular and cellularmechanisms of cardiac arrhythmias[ J ]. Cell, 2001, 104 (4) : 569
2　Williams GH, FisherND, Hunt SC, et al. Effects of gender and genotype on the phenotyp ic exp ression of nonmodulating essential hypertension[ J ]. Kidney Int, 2000, 57 (4) : 1 404
3　Tabor HK, Risch NJ, Myers RM. Candidate2gene app roaches for studying comp lex genetic traits: p ractical considerations [ J ]. NatRev Genet, 2002, 3 (5) : 391
4　KaaS, Schulze2Bahr E. Suscep tibility genes and modifiers for cardiacarrhythmias[ J ]. Cardiovasc Res, 2005, 67 (3) : 397
5　Kimbrough J,MossAJ, ZarebaW, et al. Clinical imp lications for affected parents and siblings of p robandswith long2QT syndrome[ J ].Circulation, 2001, 104 (5) : 557
6　Priori SG. Inherited arrhythmogenic diseases: the comp lexity beyond monogenic disorders[ J ]. Circ Res, 2004, 94 (2) : 140
7　Ye B,Valdivia CR, Ackerman MJ, et al. A commom human SCN5Apolymorphism modifies exp ression of an arrhythmia causingmutation[ J ]. Physiol Genomics, 2003, 12 (3) : 187
8　Viswanathan PC, Benson DW, Balser JR. A common SCN5A polymorphism modulates the biophysical effects of an SCN5A mutation[ J ]. J Clin Invest, 2003, 111 (3) : 341
9　Chen LY,Ballew JD, Herron KJ, et al. A common polymorphism in SCN5A is associated with lone atrial fibrillation[ J ]. Clin PharmacolTher, 2007, 81 (1) : 35
10　Bezzina CR, Shimizu W, Yang P, et al. Common sodium channelp romoter hap lotype in asian subjects underlies variability in cardiac conduction[ J ]. Circulation, 2006, 113 (3) : 338
11　Sesti F,Abbott GW,Wei J, et al. A common polymorphism associated with antibiotic2induced cardiac arrhythmia[ J ]. Proc Natl Acad Sci,2000, 97 (19) : 10 613
12　Kubota T, HorieM, TakanoM, et al. Evidence for a single nucleotide polymorphism in the KCNQ1 potassium channel that underlies suscep tibility to life2threatening arrhythmias [ J ]. J Cardiovasc Electrophysiol, 2001, 12 (11) : 1 223
13　Pietila E, Fodstad H,Niskasaari E, et al. Association between HERGK897T polymorphism and QT interval inmiddle2aged Finnish women[ J ]. J Am Coll Cardiol, 2002, 40 (3) : 511
14　Crotti L,LundquistAL, Insolia R, et al. KCNH22K897T is a genetic modifier of latent congenital long2QT syndrome [ J ]. Circulation,2005, 12 (9) : 1 251
15　Bezzina CR, Verkerk AO, Busjahn A, et al. A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization[ J ]. Cardiovasc Res, 2003, 59 (1) : 27
16　PfeuferA, Jalilzadeh S, Perz S, et al. Common variants in myocardialion channel genesmodify the QT interval in the general population:results from the KORA study[ J ]. Circ Res, 2005, 96 (6) : 693
17　Lai LP, SuMJ, Yeh HM, et a1. Association of the human minK gene38G allele with atrial fibrilation: evidence of possible genetic controlon the pathogenesis of atrial fibrillation [ J ]. Am Heart J, 2002, 144(3) : 485
18　Ehrlich JR, Zicha S, Coutu P, et a1. Atrial fibrillation2ssociated minK38G/S polymorphism modulates delayed rectifier current andmenbrane localization[ J ]. Cardiovasc Res, 2005, 67 (3) : 520
19　Zeng Z, Tan C, Eng S, et al. The single nucleotide polymorphisms of I(Ks) potassium channel genes and their association with atrial fibrillation in a Chinese population[ J ]. Cardiology, 2007, 108 (2) : 97
20　Ma KJ, LiN, Teng SY, et al. Modulation of KCNQ1 current by atrial fibrillation2associated KCNE4 ( 145E /D ) gene polymorphism[ J ]. ChinMed J ( Engl) , 2007, 120 (2) : 150
21　Hauer RN, Groenewegen WA, FirouziM, et al. Cx40 polymorphism in human atrial fibrillation[ J ]. Adv Cardiol, 2006, 42: 284
22　Yamashita T,HayamiN,Ajiki K, et a1. IsACE gene polymorphism asso2
ciated with lone atrial fibrillation[ J ]. Jpn Heart J, 1997, 38 (5) : 637
23　Tsai CT,Lai LP,Lin JL, et a1. Renin2angiotensin system gene polymorphisms and atrial fibrillation[ J ]. Circulation, 2004, 109 (13) : 1 640
24　Rigat B, Hubert C, Alhenc2Gelas F, et al. An insersion /deletion in the I2 gene accounting for half the variance of serum enzyme levels[ J ]. J Clin Invest, 1990, 86: 1 343
25　Marian AJ, Yu Q,Workman R, et al. Angiotensin converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiacdeath[ J ]. Lancet, 1993, 342 (8 879) : 1 085
26 　Jeron A, Hengstenberg C, Engel S, et al. The D2allele of the ACE polymorphism is related to increased QT dispersersion in 609 patients aftermyocardial infarction[ J ]. Eur Heart J, 2001, 22 (8) : 663
27　Anvari A, Turel Z, SchmidtA, et al. Angiotensin converting enzyme and angiotensinⅡreceptor 1 polymorphism in coronary disease andmalignantventricular arrhythmia[ J ]. Cardiovasc Res, 1999; 43 (4) : 879
28　Makita N, Tsutsui H. Genetic polymorphisms and arrhythmia susceptibility[ J ]. Circ J, 2007, Supp l A: A54