[ 参考文献]
[ 1 ] Allred AJ , D iz D I, Ferrario CM, et al. Pathways for angiotensin2( 127) metabolism in pulmonary and renal tissues[ J ]. Am J Physiol Renal Physiol, 2000, 279(5) : F841-850.
[ 2 ] MoriguchiA, Tallant EA,Matsumura K, et al. Opposing action of angiotensin2(1-7) and angiotensin in the brain of transgenic hypertensive rats [ J ]. Hypertension, 1995, 25 (6) : 1260-1265.
[ 3 ] Ferreira AJ , Santos RAS,Almeida AP. Angiotensin2(127) ; cardiop rotective effectin myocardial ischemia / reperfusion [ J ]. Hypertension, 2001, 38 ( part2 ) : 665-668.
[ 4 ] DonoghueM,Wakimoto H,Maguire CT, et al. Heart block, ventricular tachycar-dia, and sudden death in ACE2 transgenic mice with downregulated connexins[ J ]. J Mol Cell Cardiol, 2003, 35: 1043-1053.
[ 5 ] Kucharewicz I, Pawlak R,Matys T, et al. Antithrombotic effect of cap top ril and losartan ismediated by angiotensin2(127) [ J ]. Hypertension, 2002, 40 (5) : 774-779.
[ 6 ] Santos RA, Simoes E, Silva AC, et al. Angiotensin2(127) is an endogenous ligand for the G p rotein2coup led recep torMas[ J ]. Proc Nat Acad Sci USA, 2003,100 (14) : 8258-8263.
[ 7 ] Tallant EA, Ferrario CM, Gallagher PE. Angiotensin2( 127 ) inhibits growth of cardiac myocytes through activation of theMas recep tor[ J ]. Am J Physiol HeartCirc Physiol, 2005, 289 (4) : H1560-H1566.
[ 8 ] Castro CH, Santos RAS,Walther T, et al. Effects of genetic deletion of the G2p rotein2coup led recep torMas on cardiac function during ischemia and reperfusion in the mouse isolated perfused heart[ J ]. Hypertension, 2004, 43: 1350.
[ 9 ] Lemos VS, Silva DM,Walther T, et al. The endothelium2dependent vasodilator effect of the nonpep tide Ang(127) mimic AVE 0991 is abolished in the aorta of Masknockoutmice[ J ]. Cardiovasc Pharmaco1, 2005, 46 (3) : 274-279.
[ 10 ] Tallant EA, ChappellMC, Ferrario CM, et al. Inhibition ofMAP kinase activity by angiotensin-(1-7) in vascular smooth muscle cells is mediated by theMasrecep tor[ J ]. Hypertension, 2004, 43: 1348.
[ 11 ] L iu CQ, Huang Y, Lu LM. Effects of ACE22Ang 1272Mas axis on blood vessel[ J ]. Sheng L i Ke Xue J in Zhan, 2007, 38 (1) : 43-48.
[ 12 ] Silva DM,Vianna HR, Cortes SF, et al. Evidence for a new angiotensin-(1-7)recep tor subtype in the aorta of Sp rague2Dawley rats [ J ]. Pep tides, 2007, 28(3) : 702-707.
[ 13 ] Shieffer B, Schieffer E, Hilfiker2Kleiner D, et al. Exp ression of angiotensin Ⅱand interleukin 6 in human coronary atherosclerotic p laques [ J ]. Circulation,2000, 101: 1372-1378.
[ 14 ] Kranzhofer R, Schmidt J , Pfeiffer CAH, et al. Angiotensin induces inflammatory activation of human vascular smoothmuscle cells[ J ]. A rterioscler ThrombVasc Biol, 1999, 19: 1623-1629.
[ 15 ] Pastore L, Tessitore A,Martinotti S, et al. AngiotensinⅡstimulates intercellular adhesion molecule21 ( ICAM21) exp ression by human vascular endothelial cellsand increases soluble ICAM21 release in vivo [ J ]. Circulation, 1999, 100: 1646-1652.
[ 16 ] UsuiM, Egashira K, Tomita H, et al. Important role of local angiotensinⅡ activitymediated via type 1 recep tor in the pathogenesis of cardiovascular inflammatory changes induced by chronic blockade of nitric oxide synthesis in rats[ J ].Circulation, 2000, 101: 305-2310.
[ 17 ] Tham DM,Martin2McNulty B,Wang YX, et al. Angiotensin Ⅱ is associated with activation of NF2кB2mediated genes and downregulation of PPARs [ J ].Physiol Genomics, 2002, 11: 21-30.
[ 18 ] Sakamoto H, Aikawa M, Hill CC, et al. B iomechanical strain induces class Ascavenger recep tor exp ression in human monocyte /macrophages and THP2lcells: a potential mechanism of increased atherosclerosis in hypertension [ J ].Circulation, 2001, 104: 109-114.
[ 19 ] B rewster JL, de Valoir T,Dwyer NC, et al. An osmosensing signal transduction pathway in yeast[ J ]. Science, 1993, 259 (5102) : 1760-1763.
[ 20 ] Boder AJ , Ye R, Lees2Miller SP. U2light induces p38MAPK2dependent phosphorylation ofBel 10 [ J ]. B iochem B iophys Res Commun, 2003, 301 (4) : 923-926.
[ 21 ] TaroM, Ingela T,Majlis B, et al. p38MAPK kinase negatively regulates endothelial cell survival, p roliferation, and differentiation in FGF222stimulated angiogenesis[ J ]. J CellB iol, 2002, 156 (1) : 149-160.
[ 22 ] Chakravortty D, Kato Y, Koide N, et al. Extracellularmatrix component preventlipopolysaccharide2induced bovine arterial endothelial cell injury by inhibiting
p38 mitogen2activated p rotein kinase [ J ]. Thromb Res, 2000, 98 (2) : 187-189.
[ 23 ] Mu JY, Chen XG. The p rogress of the study on themitogen2activated p rotein kinase pathways[ J ]. Chin Bull L ife Sci, 2002, 14 (4) : 208-211.
[ 24 ] Obata T, B rown GE, Yaffe MB. MAP kinase pathways activated by stress: the p38MAPK pathway[ J ]. Crit CareMed, 2000, 28 (1) : 67-77.
[ 25 ] J iang Y, L iu AN, Huang QB, et al. p38MAPK signal is necessary for TNF-αgene exp ression in RAW cells[ J ]. Acta B iochim B iophys Sin, 1999, 31 (1) : 9-15.
[ 26 ] J iang Y,L iu AN, ZhangL, et al. Activation of p38 mitogen2activated p rotein kinase induced by lipopolysaccharide and its the in TNF-αgene exp ression[ J ]. JMed Coll PLA, 1999, 14 (2) : 138-143 ( in Chinese).
[ 27 ] ZhaoM,L iu YW, L iu AH, et al. Signal transduction in TNF-αinducted c-jungene exp ression[ J ]. Acta B iochim B iophys Sin, 2000, 32 (3) : 59265 ( in Chinese with English abstract).
[ 28 ] Guan Z, Baier LD,Morrison AR. p38 mitogen2activated p rotein kinase downregulates nitric oxide and up regulate sp rostaglandin E2 biosynthesis stimulated by interleukin21beta[ J ]. J B iol Chem, 1997, 272 (12) : 8083-8089.
[ 29 ] ReadMA,WhitleyMZ, Gup ta S, et al. Tumor necrosis factor alpha2induced Eselectin exp ression is activated by the nuclear factor2kappa B and c2Jun N2terminal kinase /p38 mitogen2activated p rotein kinase pathways[ J ]. J B iol Chem,1997, 272 (5) : 2753-2761.
[ 30 ] Guan Z,Buckman SY,MillerBW, et al. Interleukin21 beta induced cyclooxygenase22 exp ression requires activation of both c2Jun NH22terminal kinase and p38MAPK signal pathways in rat renal messangial cells [ J ]. J B iol Chem,1998, 273 (44) : 28670-28676.
[ 31 ] ClarkMA,Diz DL, Tallant EA. Angiotensin2(127) downregulates the angiotensin Ⅱ type 1 recep tor in vascular smoothmuscle cells[ J ]. Hypertension, 2001,37 (4) : 1141-1146.
[ 32 ] Kostenis E,Milligan G, Christopoulos A, et al. G2p rotein2coup led recep torMasis a physiological antagonist of the angiotensin Ⅱ type 1 recep tor [ J ]. Circulation, 2005, 111: 1806-1813.
[ 33 ] W illiam B, Strawn CM, Ferrario EA. Angiotensin2(127) reduces smooth muscle growth after vascular injury[ J ]. Hypertension, 1999, 33 (1) : 207-211.
[ 34 ] 曾武涛,马 虹,鲁 伟,等. 血管紧张素2(127)在血管紧张素Ⅱ诱导心肌细胞肥大中的作用[ J ]. 中华心血管病杂志, 2000, 28 (6) : 460-463.
[ 35 ] 李晓东,尹德录,叶 琳,等. 血管紧张素2(127)拮抗血管紧张素Ⅱ对钾通道的作用[ J ]. 中国心脏起搏与心电生理杂志, 2004, 18 (1) : 52-56.
[ 36 ] 李晓东,尹德录,蒋文平. 血管紧张素2(127)对豚鼠心肌细胞电生理作用的研究[ J ]. 中华心血管病杂志, 2002, 30 (2) : 105-108.
[ 37 ] Guo RW, Yang LX,L iMQ, et al. Angiotensin Ⅱ inducesNF2kappaB activation in HUVEC via the p38 MAPK pathway [ J ]. Pep tides, 2006, 27 ( 12 ) : 3269-3275.
[ 38 ] 娄 宁,余学清,祝胜郎,等. 血管紧张素Ⅱ激活巨噬细胞株p38MAPK信号通路并诱导其增殖[ J ]. 中国免疫学杂志, 2005, 21 (6) : 416-420.
[ 39 ] Naito T,Masaki T,Nikolic2Paterson DJ. Angiotensin Ⅱ induces thrombospondin21 p roduction in human mesangial cells via p38MAPK and JNK: a mechanism for activation of latent TGF-β1 [ J ]. Am J Physiol Renal Physiol, 2004,286: F278-F287.
[ 40 ] Zheng J ,Wen YX, Chen DB, et al. Magness angiotensin Ⅱ elevates nitric oxidesynthase 3 exp ression and nitric oxide p roduction via a mitogen2activated p rotein kinase cascade in ovine fetop lacental artery endothelial cells[ J ]. B iol Rep rod, 2005, 72: 1421-1428.
[ 41 ] 李 莉,高平进,沈伟利,等. 血管紧张素Ⅱ诱导自发性高血压大鼠血管外膜成纤维细胞迁移活性涉及p38 MAPK[ J ]. 中华心血管病杂志, 2005, 33(6) : 557-560.
[ 42 ] Su Z, Zimpelmann J , Burns KD. Angiotensin2( 127 ) inhibits angiotensin Ⅱstimulated phosphorylation ofMAP kinases in p roximal tubular cells[ J ]. Kidney Int, 2006, 69 (12) : 2212-2218.
来源:心血管病学进展 作者:梁长清,杨志明,肖传实