心力衰竭分子机制的研究进展

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[ 1 ] 　Shyy JYJ , Chien S. Role of integrins in endothelialmechanosensing of shear stress[ J ]. Circ Res, 2002, 91 (9) : 769-775.
[ 2 ] 　Babbitt CJ , Shai SY, HarpfAE, et al. Modulation of integrins and integrin signalingmolecules in the p ressure2loaded murine ventricle[ J ]. Histochem CellB iol,2002, 118 (6) : 431-439.
[ 3 ] 　Aikawa R, Nagai T, Kudoh S, et al. Integrins p lay a critical role in mechanical stressinduced p38MAPK activation[ J ]. Hypertension, 2002, 39 (2) : 233-238.
[ 4 ] 　Krishnamurthy P, Subramanian V, SinghM, et al. Beta1 integrinsmodulate betaadrenergic recep tor2stimulated cardiac myocyte apop tosis and myocardial remodeling[ J ]. Hypertension, 2007, 49 (4) : 767-768.
[ 5 ] 　Antos CL, Frey N,Marx SO, et al. Dilated cardiomyopathy and sudden death resulting from constitutive activation of p rotein kinase A [ J ]. Circ Res, 2001, 89(11) : 997-1004.
[ 6 ] 　Appert2Collin A, Cotecchia S,Nenniger2TosatoM, et al. The A2kinase anchoringp rotein (AKAP) 2Lbc2signaling comp lexmediates alpha1 adrenergic recep tor2induced cardiomyocyte hypertrophy[ J ]. Proc NatlAcad SciUSA, 2007, 104 (24) :10140-10145.
[ 7 ] 　Maack C, Kartes T, Kilter H, et al. Oxygen free radical release in human failing myocardium is associatedwith increased activity of rac12GTPase and rep resents atarget for statin treatment[ J ]. Circulation, 2003, 108 (13) : 1567-1574.
[ 8 ] 　Heymes C,Bendall JK, Ratajczak P, et al. Increased myocardialNADPH oxidase activity in human heart failure [ J ]. J Am Coll Cardiol, 2003, 41 ( 12 ) : 2164-2171.
[ 9 ] 　Bendall JK, Cave AC, Heymes C, et al. Pivotal role of a gp91 (phox) 2containing NADPH oxidase in angiotensin Ⅱ2induced cardiac hypertrophy in mice[ J ]. Circulation, 2002, 105 (3) : 293-296.
[ 10 ] 　Cheng TH, Cheng PY, Shih NL, et al. Involvement of reactive oxygen species in angiotensin Ⅱ2induced endothelin21 gene exp ression in rat cardiac fibroblasts[ J ]. J Am Coll Cardiol, 2003, 42 (10) : 1845-1854.
[ 11 ] 　SunM, ChenM,Dawood F, et al. Tumor necrosis factor2alpha mediates cardiac remodeling and ventricular dysfunction after p ressure overload state [ J ]. Circulation, 2007, 115 (11) : 1398-1407.
[ 12 ] 　Haudek SB, Taffet GE, SchneiderMD, et al. TNF p rovokes cardiomyocyte apoptosis and cardiac remodeling through activation of multip le cell death pathways[ J ]. J Clin Invest, 2007, 117 (9) : 2692-2701.
[ 13 ] 　Podewski EK, Hilfiker2KleinerD, Hilfiker A, et al. Alterations in Janus kinase(JAK) 2signal transducers and activators of transcrip tion ( STAT) signaling inpatientswith end2stage dilated cardiomyopathy[ J ]. Circulation, 2003, 107 (6) :798-802.
[ 14 ] 　Matsushita K, Iwanaga S, Oda T, et al. Interleukin26 / soluble interleukin26 recep tor comp lex reduces infarct size via inhibitingmyocardial apop tosis[ J ]. LabInvest, 2005, 85 (10) :1210-1223.
[ 15 ] 　Zou Y, Takano H,MizukamiM, et al. Leukemia inhibitory factor enhances survival of cardiomyocytes and induces regeneration ofmyocardium aftermyocardial infarction[ J ]. Circulation, 2003, 108 (6) : 748-753.
[ 16 ] 　Freed DH, Cunnington RH, Dangerfield AL, et al. Emerging evidence for therole of cardiotrophin21 in cardiac repair in the infarcted heart [ J ]. CardiovascRes, 2005, 65 (4) :782-792.
[ 17 ] 　TakahashiN, Saito Y, Kuwahara K, et al. Hypertrophic responses to cardiotrophin-1 are notmediated by STAT3, but via aMEK52ERK5 pathway in cultured cardiomyocytes[ J ]. J Mol Cell Cardiol, 2005, 38 (1) : 185-192.
[ 18 ] 　Foo RS,Mani K, Kitsis RN. Death begets failure in the heart[ J ]. J Clin Invest,2005, 115 (3) : 565-571.
[ 19 ] 　Merkle S, Frantz S, SchênMP, et al. A role for caspase21 in heart failure [ J ].Circ Res, 2007, 100 (5) : 645-653.
[ 20 ] 　Sharov VG, TodorA, Suzuki G, et al. Hypoxia, angiotensin2Ⅱ, and norep inephrine mediated apop tosis is stimulus specific in canine failed cardiomyocytes: arole for p38MAPK, Fas2L and cyclin D [ J ]. Eur J Heart Fail, 2003, 5 ( 2 ) :121-129.
[ 21 ] 　Ravassa S, FortunoMA, GonzalezA, et al. Mechanisms of increased suscep tibility to angiotensin Ⅱ2induced apop tosis in ventricular cardiomyocytes of spontaneously hypertensive rats[ J ]. Hypertension, 2000, 36 (6) : 1065-1071.